In a healthy individual, alveolar dead space is zero. Alveolar dead space is the volume of air that fills the gas exchanging regions of the lung but does not participate in gas exchange. Physiological dead space is the combination of anatomical dead space plus alveolar dead space. Anatomical dead space is the volume of air that is in the conducting zone of the lung. Anatomical dead space and physiological dead space are two ways of defining the lung dead space. Lung dead space is the portion of the tidal volume that does not participate in gas exchange. Summary – Anatomical vs Physiological Dead Space Therefore, this is another difference between anatomical and physiological dead space. In contrast, physiological dead space includes the air that penetrates into gas exchange regions. But, physiological dead space becomes larger under disease conditions.Īnatomical dead space does not include the air that penetrates into gas exchange regions. The average value of anatomical dead space is 150 mL, while the normal value of physiological dead space is also150 mL. So, this is the key difference between anatomical and physiological dead space. Meanwhile, physiological dead space is the sum of all parts of the tidal volume that does not participate in gas exchange. What is the Difference Between Anatomical and Physiological Dead Space?Īnatomical dead space is the air-filled in conducting airways and does not participate in gas exchange.
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